Browsing Internal Medicine by Title
Now showing items 1-20 of 57
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An analysis of pregnancy-related mortality in the KEMRI/CDC health and demographic surveillance system in western Kenya
(Public Library of Science, 2013)Background: Pregnancy-related (PR) deaths are often a result of direct obstetric complications occurring at childbirth. Methods and Findings: To estimate the burden of and characterize risk factors for PR mortality, we ... -
Anna M van Eijk, Peter O Ouma, John Williamson, Feiko O Ter Kuile, Monica Parise, Kephas Otieno, Mary J Hamel, John G Ayisi, Simon Kariuki, Piet A Kager, Laurence Slutsker
(The University of Chicago Press, 2008)Sulfadoxine-pyrimethamine (SP) inhibits folate metabolism by the malaria parasite.We investigated the association between folate levels and SP failure in pregnant women. Data from a trial to assess the effect that folate ... -
Antenatal and delivery care in rural western Kenya: the effect of training health care workers to provide" focused antenatal care"
(BioMed Central, 2010)Background Maternal mortality remains high in developing countries and data to monitor indicators of progress in maternal care is needed. We examined the status of maternal care before and after health care worker (HCW) ... -
Antifolate Resistance in Plasmodium falciparum: Multiple Origins and Identification of Novel dhfr Alleles
(The University of Chicago Press, 2006)BackgroundSulfadoxine-pyrimethamine has been widely used as first-line therapy for uncomplicated malaria throughout sub-Saharan Africa. Recent studies conducted in Asia and Africa suggest the triple-mutant dhfr genotype ... -
An assessment of effectiveness of drug rehabilitation programs in Kisii County-Kenya
(Health Education Research & Development, 2016)According to the World Drug Report, approximately 200 million people, about 5% of the World’s population aged between 15 and 64 years have either been forced or voluntarily sought the help of rehabilitation centers for ... -
Barriers and facilitators to antenatal and delivery care in western Kenya: a qualitative study
(BioMed Central, 2015)Background In western Kenya, maternal mortality is a major public health problem estimated at 730/100,000 live births, higher than the Kenyan national average of 488/100,000 women. Many women do not attend antenatal care ... -
Birth preparedness and complication readiness among women attending antenatal care clinic in health facilities within Bureti sub county of Kericho county, Kenya
(2016)Maternal mortality remains a major public health problem in Kenya with 488 deaths per 100,000 live births. Birth preparedness and complication readiness is one of the recommended strategies by the major global initiatives ... -
Burden of disease and risk factors for mortality amongst hospitalized newborns in Nigeria and Kenya
(Public Library of Science, 2021)Objective To describe the patient population, priority diseases and outcomes in newborns admitted <48 hours old to neonatal units in both Kenya and Nigeria. Study design In a network of seven secondary and tertiary ... -
Case report: Acute Kidney Injury, Liver impairment, Severe Anemia in a child with Malaria and Hyperparasitaemia
(Global Journal of Medical and Clinical Case Report, 2021)Severe Malaria is a medical emergency mainly because of its rapid progression to complications and death if not promptly and adequately treated. In 2018 WHO put the incidence of P. falciparum Malaria in the African region ... -
Clinical laboratory hematology reference values among infants aged 1month to 17 months in Kombewa Sub-County, Kisumu: A cross sectional study of rural population in Western Kenya
(Public Library of Science, 2021)There is an urgent need for reliable region-specific hematological reference values for clinical monitoring. Laboratory reference ranges are important for assessing study participant eligibility, toxicity grading and ... -
Community perceptions of mass screening and treatment for malaria in Siaya County, western Kenya
(BioMed Central, 2016)Intermittent mass screening and treatment (iMSaT) is currently being evaluated as a possible additional tool for malaria control and prevention in western Kenya. The literature identifying success and/or barriers to drug ... -
A comparative performance of indigenous chicken in Baringo and Kisumu Counties of Kenya for sustainable agriculture
(2016)The population of the world continues to increase especially in developing countries calling for increased food production which puts great pressure to develop a more sustainable agricultural economic activity throughout ... -
COVID-19 pandemic: impacts on the achievements of Sustainable Development Goals in Africa
(Pan African Medical Journal, 2021)Since the launch of the Sustainable Development Goals (SDGs) in 2015, Africa has made some progress towards its achievements, particularly in the area of gender equality- SDG 5, climate change -SDG 13 and preserving ... -
A cross-sectional study of the availability and price of anti-malarial medicines and malaria rapid diagnostic tests in private sector retail drug outlets in rural Western Kenya …
(BioMed Central, 2016)Background Although anti-malarial medicines are free in Kenyan public health facilities, patients often seek treatment from private sector retail drug outlets. In mid-2010, the Affordable Medicines Facility-malaria (AMFm) ... -
Cytopenia among CML Patients on Imatinib in Kenya: Types, Grades, and Time Course
(Hindawi, 2020)Imatinib mesylate is the gold standard for the treatment of all phases of Philadelphia-positive chronic myeloid leukemia. Patients on imatinib treatment may develop cytopenia due to drug toxicity. *is study aimed to ... -
Delay Along the Care Seeking Journey of Patients with Microbial Keratitis in Uganda
(Taylor & Francis, 2019)PURPOSE To describe the care seeking journey and causes of delay among patients with Microbial Keratitis in Uganda. METHODS A prospective cohort of patients presenting with microbial keratitis at the two main eye units ... -
Dihydrofolate reductase I164L mutations in Plasmodium falciparum isolates: clinical outcome of 14 Kenyan adults infected with parasites harbouring the I164L …
(Royal Society of Tropical Medicine and Hygiene, 2008)Recently, Plasmodium falciparum bearing dihydrofolate reductase (DHFR) I164L was isolated from Africa. Quadruple mutations containing I164L confer high-level resistance to antifolate antimalarials. We prospectively measured ... -
Does cotrimoxazole prophylaxis for the prevention of HIV-associated opportunistic infections select for resistant pathogens in Kenyan adults?
(The American Society of Tropical Medicine and Hygiene, 2008)We assessed the effect of daily cotrimoxazole, essential for HIV care, on development of antifolateresistant Plasmodium falciparum, naso-pharyngeal Streptococcus pneumoniae (pneumococcus), and commensal Escherichia coli. ... -
The effect of health care worker training on the use of intermittent preventive treatment for malaria in pregnancy in rural western Kenya
(Blackwell Publishing Ltd, 2007)background In 1998, Kenya adopted intermittent preventive treatment (IPTp) with sulphadoxinepyrimethamine (SP) for malaria prevention during pregnancy. We conducted a survey in 2002 among women who had recently delivered ... -
Effect of malaria rapid diagnostic tests on the management of uncomplicated malaria with artemether-lumefantrine in Kenya: a cluster randomized trial
(The American Society of Tropical Medicine and Hygiene, 2009)Shortly after Kenya introduced artemether-lumefantrine (AL) for first-line treatment of uncomplicated malaria, we conducted a pre-post cluster randomized controlled trial to assess the effect of providing malaria rapid ...